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Superior technology solutions for cell line development.
A complete, cutting-edge cell counting and monitoring platform
Comprehensive hardware, software, and data management solutions that enhance the techniques, efficiency, and accuracy of cell line development.
At a Glance: Our Cell Counting and Monitoring Platform
Microplate Imaging Hardware:
- Custom designed for our imaging method and artificial intelligence
- Supports standard microplates up to 384 wells with clear and flat well bottom
- No focusing setup required; captures cells on multiple focal planes
- Full 96/384 well microplate imaging in about 30 minutes
Cell Counting:
- Currently over 98% accurate (total cell count)
- Live/dead cell counting without labels
- Automatically divides cell cultures into distinct populations and culture similarity scoring
Data Storage & Management:
- Central storage server (deployed internally alongside imaging hardware); scalable with the addition of extra modules and access from other computers
- Traceability of cells and cultures over time and process
- Analysis engine: Cell fingerprinting using custom-built artificial intelligence; cell culture comparison that goes beyond simple optical properties
- Investigation of hidden similarities between different cells/cultures
Advanced Cell Counting
Our patented technology advantages include:
- Advanced AI-assisted optical image recognition
- Noninvasive cell viability
- Rapid cell imaging via our proprietary optic system
- In-house closed loop motion control
- Plate and sample traceability
- Internal environmental monitoring
- Tightly coupled illumination and capture
- Scalable device connectivity and data sharing
- Intuitive and rich user interface
DeepInsight™
With our advanced image recognition, artificial intelligence (AI), and deep learning technology, we can predict early-stage cell colonies and viability.
- Prediction of a viable cell culture from a single day zero cell
- AI allows us to predict cell viability with noninvasive techniques
- Deep insights to cell properties built on our data storage platform
- The quality of the data from our custom hardware and optics platform lets us maximize AI capabilities
- Our ongoing platform development will allow us to realize additional AI opportunities
- Our hardware, optics, and software platform has been designed from the ground up to integrate AI and deep learning capabilities.
With focal plane invariant imaging (Z Stack), a system focus setup is not required. This imaging provides a wealth of data and is the bedrock for our state-of-the-art artificial intelligence cell analysis platform.
DeepInsight automatically reduces the stack into a single image, even if cells lie on different focal planes. Cells do not need to be fluorescently labeled for accurate cell counts.
Individual cells are identified and highlighted using our bespoke AI platform. Cell clusters, doublets, even cells within debris are counted accurately. Cell viability is predicted for each individual cell.
- High accuracy cell counting across multiple focal planes
- Viability scoring of individual cells
- Culture population segmentation and cell similarity scoring
As part of our long-term vision, we are developing additional biotech solutions based on our patented imaging and data management technologies.
Microfluidics and advanced technologies:
- Microfluidics-based cell visibility with Trypan Blue
- Using our AI imaging technology
- Establish control system for manufacture of PMMA-based microfluidics
- Develop low-cost microfluidics counter
High throughput microfluidics:
- Multi-chip system with camera shuffle
- Fluorescent luminescence for mixing-based assays
Experimental cell sorting systems:
- R&D alternative cell sorting and manipulation systems on chip
Data storage technologies:
- Data verification through sequential encryption hashing
- Petabyte backup systems and data verification
- Secure remote access API
- Hybrid cloud storage nodes for horizontal scalability
- Advance data compression techniques for data size reduction
UK Operations center:
Design & Engineering, Manufacturing, R&D & data center.
TEK Optima Research Ltd -UK
Unit 10 Westcroft Business Park,
Oakdene Drive, Three Legged Cross,
Wimborne BH21 6FQ,
United Kingdom.
Email: [email protected]
Phone: +44 (0) 1202 942105
North America Operation center:
Customer service center, R&D & data center.
TEK Optima Research – North America
800 Park Offices Drive,
Suite 3617,
Research Triangle Park,
NC 27709. USA
Email: [email protected]
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